Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

capsaicin, lidocaine, menthol, and methyl salicylate (topical)

Pronunciation: kap SAY sin, LYE doe kane, MEN thol, and METH il sa LIS i late

Brand: LidoPro, Terocin, Transderm-iQ

What is the most important information I should know about this medicine?

You should not use this medicine if you are allergic to aspirin, sulfa drugs, PABA (para-aminobenzoic acid).

What is capsaicin, lidocaine, menthol, and methyl salicylate?

Capsaicin, lidocaine, menthol, and methyl salicylate topical (for the skin) is a combination medicine used for temporary relief of muscle pain and soreness than may be related to arthritis, strains, backaches, or bruises.

Capsaicin, lidocaine, menthol, and methyl salicylate topical may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using this medicine?

You should not use this medicine if you are allergic to:

  • aspirin;
  • sulfa drugs; or
  • sunscreen or other skin products that contain para-aminobenzoic acid (PABA).

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

  • sensitive skin;
  • an allergy to chili peppers;
  • a blood cell disorder called methemoglobinemia (in you or a family member);
  • heart problems;
  • breathing problems; or
  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Ask a doctor before using this medicine if you are pregnant or breastfeeding. If you apply the medicine to your chest, avoid areas that may come into contact with the baby's mouth.

Do not use this medicine on a child without medical advice. Capsaicin, lidocaine, menthol, and methyl salicylate is not approved for use by anyone younger than 12 years old.

How should I use this medicine?

Use exactly as directed on the label, or as prescribed by your doctor.

Do not take by mouth. Topical medicine is for use only on the skin.

Do not use on open wounds or on broken or infected skin. If this medicine gets in your eyes, nose, mouth, rectum, or vagina, rinse with water.

Wash your hands with soap and water immediately after applying this medicine.

This medicine can cause a burning sensation wherever it is applied. This sensation is usually mild and should gradually lessen over time with continued regular use of the medicine.

If the burning sensation is painful or causes significant discomfort, wash the treated skin area with soap and cool water. Get medical attention right away if you have severe burning, pain, redness, or skin irritation.

Shake the lotion before each use.

Do not cover treated skin with a bandage or heating pad, which can increase the burning sensation.

Call your doctor if your pain does not improve after using this medicine for 7 days, or if your symptoms get worse.

To keep this medicine from getting on your fingers when you apply it, you may use a rubber glove, finger cot, cotton ball, or clean tissue to apply the medicine.

Store the medicine at room temperature away from moisture and heat, in a place where children and pets cannot get to it.

What happens if I miss a dose?

Since capsaicin, lidocaine, menthol, and methyl salicylate is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

Do not use this medicine more than 4 times per day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222, especially if anyone has accidentally swallowed it.

What should I avoid while using this medicine?

Do not get this medicine in your eyes, mouth, nose, genitals, or rectum. If contact does occur, rinse with water. Avoid touching these areas until the medicine has been washed off your hands.

Avoid using other medications on the areas you treat with capsaicin, lidocaine, menthol, and methyl salicylate unless your doctor tells you to.

What are the possible side effects of this medicine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Wash the skin and get medical attention right away if you have severe burning, pain, swelling, or blistering of the skin where you applied this medicine.

Stop using this medicine and call your doctor at once if you have:

  • pale skin, blue-colored lips;
  • headache, confusion; or
  • rapid heartbeats.

Common side effects may include a mild burning sensation that can last for several hours or days, especially after your first use of this medicine.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect capsaicin, lidocaine, menthol, and methyl salicylate?

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Where can I get more information?

Your pharmacist can provide more information about capsaicin, lidocaine, menthol, and methyl salicylate topical.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 1.02. Revision date: 12/16/2019.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.

phone number