For preventing gout.
Brand Name(s): Duzallo
Generic Name: Allopurinol/Lesinurad
Take the medicine with food.
Do not take on an empty stomach.
Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.
This medicine will work best if you take it at about the same time every day.
Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.
Drink extra water while on this medicine. Adults should try to drink 6-8 cups (48 to 64 oz.) of water every day.
It may take several weeks for this medicine to fully work.
It is important that you keep taking each dose of this medicine on time even if you are feeling well.
If you forget to take a dose on time, return to your normal dosing schedule on the following day.
Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.
Tell your doctor if symptoms do not get better or if they get worse.
Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.
This medicine may decrease the effectiveness of some birth controls which use hormones (such as birth control pills and patches). Use an extra form of birth control, such as condoms, while on this medicine.
Keep all appointments for medical exams and tests while on this medicine.
Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.
This medicine is associated with an increased risk of serious heart problems, heart attack, and stroke. Please speak with your doctor about the risks and benefits of using this medicine. Contact your doctor immediately if you experience chest pain or difficulty breathing.
Gout attacks may occur for a few months after starting this medicine. Do not stop taking this medicine if gout attacks occur. Your doctor may add another medicine to treat the attacks.
Do not use the medication any more than instructed.
This medicine may cause dizziness or fainting, especially after exercising or in hot weather. Be very careful when standing or sitting up quickly.
If possible, avoid using with marijuana or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.
Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.
Speak with your doctor before taking any medicine with aspirin.
Please check with your doctor before drinking alcohol while on this medicine.
Contact your doctor if you notice a change in the amount or darkening of your urine.
Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.
Do not share this medicine with anyone who has not been prescribed this medicine.
Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.
The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.
- drowsiness or sedation
- stomach upset or abdominal pain
Call your doctor or get medical help right away if you notice any of these more serious side effects:
- back pain
- bleeding or bruising
- chest or jaw pain
- numbness or tingling in hands and feet
- signs of kidney damage (such as change in urine color or bubbly urine)
- signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
- red, burning, or itchy skin
- symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
- excessive or unusual sweating
- difficulty or discomfort urinating
- vaginal bleeding or spotting between periods
- unexpected or extreme weight loss
A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.
Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.
IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.
There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.
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