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Estradiol Cypionate Injectable Solution 5 mg/mL (ESTRADIOL CYPIONATE - INJECTION)

This medicine is used for the following purposes:

  • endocrine disorder
  • menopausal symptoms
  • cancer

Brand Name(s): Depo-estradiol

Generic Name: Estradiol Cypionate

Instructions

This medicine is given as an injection into a muscle.

Read and make sure you understand the instructions for measuring dose and using syringe. If you have any questions, talk to your doctor, nurse, or pharmacist.

Always inspect the medicine before using.

Do not use the medicine if it contains any particles or if it has changed color.

Shake well to dissolve any visible particles. Do not use if particles do not disappear.

Keep medicine at room temperature. Protect from light.

Never use any medicine that has expired.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

This medicine may cause dark patches to appear on your face. Avoid sunlight and use sunscreen lotion to minimize further darkening of these skin patches.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine may increase the risk of cancer. Ask your doctor about the benefits and risks.

This medicine is associated with an increased risk for serious blood clots. Speak with your doctor about the benefits and risks from using this medicine.

Do not use the medication any more than instructed.

Avoid smoking while on this medicine. Smoking may increase your risk for stroke, heart attack, blood clots, high blood pressure, and other diseases of the heart and blood vessels.

Ask your doctor how to do a breast self-exam. Check monthly. Report any changes to your doctor.

Talk to your doctor about getting a complete physical exam every year while on this medicine.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not use this medicine if you are pregnant. If you become pregnant, contact your doctor immediately.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • bloating
  • breast pain or swelling
  • headaches
  • pain, redness, swelling near injection
  • dark patches on skin or face
  • nausea and vomiting
  • weight gain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • breast lump or discharge
  • chest or jaw pain
  • depression or feeling sad
  • swelling of the legs, feet, and hands
  • fainting
  • severe or persistent headache
  • sudden leg pain, swelling, warmth or redness
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • shortness of breath
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • excessive thirst
  • increased urinary frequency
  • cramping of the uterus or bleeding from the vagina
  • vaginal itching or discharge
  • blurring or changes of vision
  • severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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