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Carbidopa/Entacapone/Levodopa Oral Tablet (CARBIDOPA/LEVODOPA/ENTACAPONE - ORAL)

For Parkinson's disease.

Brand Name(s): Stalevo

Generic Name: Carbidopa/Entacapone/Levodopa

Instructions

Swallow the medicine without crushing or chewing it.

You may take with food to prevent stomach upset.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Do not take vitamins or supplements containing iron within two hours of taking this medicine.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

If you stop this medicine suddenly after using it regularly for a long time, you may have withdrawal. Your doctor may slowly reduce your dose before stopping it. Tell your doctor right away if you notice any symptoms of withdrawal. Withdrawal symptoms can include anxiety, depression, confusion, fever, or muscle stiffness.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine may cause serious bleeding from the stomach or bowels. Stop this medicine and call your doctor immediately if you see any signs of bleeding. Bleeding can cause pain in the stomach, vomiting up liquid that looks like coffee grounds, and red or dark tarry stools.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting, especially after exercising or in hot weather. Be very careful when standing or sitting up quickly.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

If you drink more than a few alcoholic beverages each day, ask your doctor whether you should be on this medicine.

Call the doctor if there are any signs of confusion or unusual changes in behavior.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • agitated feeling or trouble sleeping
  • decreased appetite
  • diarrhea
  • changes in the color of the urine or stool
  • dizziness or drowsiness
  • bad dreams
  • dry mouth
  • lack of energy and tiredness
  • headaches
  • low blood pressure
  • nausea and vomiting
  • stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • change in behavior
  • unusual bruising or discoloration on skin
  • chest pain
  • confusion
  • coughing up blood or vomit that looks like coffee grounds
  • depression or feeling sad
  • severe, watery or bloody diarrhea
  • increased eye blinking or twitching
  • pain in the eye
  • fainting
  • high fever
  • flu-like symptoms
  • numbness or tingling in hands and feet
  • hallucinations (unusual thoughts, seeing or hearing things that are not real)
  • fast or irregular heart beats
  • unusual strong urges - such as increased need to shop, gamble, or have sex
  • mood changes
  • uncontrollable movement of face, tongue, arms or legs
  • muscle aches, spasms or abnormal movements
  • dark, tarry stool
  • unusual or unexplained tiredness or weakness
  • urinating less often
  • dark urine
  • blurring or changes of vision

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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